Muscle biopsy is a medical procedure that involves the removal of a small piece of muscle tissue for diagnosis. There are some other terms that can be used interchangeably with muscle biopsy that have similar meanings. These include muscle sampling, muscle aspiration, myoblast biopsy, and muscle needle biopsy. These terms are commonly used to describe the procedure of collecting muscle tissue to diagnose various diseases such as muscular dystrophy or myositis. Ultimately, regardless of the terminology used, a muscle biopsy is a valuable tool in diagnosis and treatment of muscle disorders and can provide important information for a patient's medical team to create a more effective treatment plan.