Quadruplication is a word that describes the act or process of multiplying something four times. However, there are several synonyms available that can be used instead of quadruplication. Some of the synonyms for quadruplication are tetrad, quadruple, quadrupling, quad, and quadruped. Tetrad is a term that is used in biology, and it describes a set of four cells. Quadruple is often associated with numbers and refers to four times the size or quantity of something. Quadrupling is the act of increasing something four times, while quad and quadruped are more commonly associated with animals that have four limbs like dogs, cats, and horses.