Space cases can refer to those who exhibit rather unusual or eccentric behavior, particularly when venturing into the unknown or trying something new. Other synonyms for space cases might include oddballs, unconventional thinkers or creatives, or even eccentric personalities. These individuals may be known for their unique view of the world, or highly creative or artistic abilities. They might also be referred to as free thinkers, mystics, and even mystics or cosmic travelers. Ultimately, space cases are those who see the world in a different light and approach life with an open and uninhibited perspective.